Host biomarkers for monitoring therapeutic response in extrapulmonary tuberculosis
نویسندگان
چکیده
منابع مشابه
Circulating biomarkers of pulmonary and extrapulmonary tuberculosis in children.
Tuberculosis (TB) in children is not only more likely to cause more severe disease than that seen in adults, it is also more likely to be extrapulmonary. Moreover, pediatric TB is very difficult to diagnose and suffers from a lack of understanding of host biomarkers for monitoring the progression of disease. Hence, we sought to identify the expression patterns of a variety of biomarkers in the ...
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Invasive pulmonary aspergillosis (IPA) is a life-threatening disease of immunocompromised patients that requires aggressive therapy. Detection of the disease and monitoring of the therapeutic response during IPA are complex, and current molecular diagnostics are not suitably robust. Here, we explored proteomic profiles of bronchoalveolar lavage fluid (BALF) specimens from a persistently neutrop...
متن کاملExtrapulmonary tuberculosis
316 Tuberculosis can involve any organ system in the body. While pulmonary tuberculosis is the most common presentation, extrapulmonary tuberculosis (EPTB) is also an important clinical problem. The term EPTB has been used to describe isolated occurrence of of tuberculosis at body sites other than the lung. However, when an extrapulmonary focus is evident in a patient with pulmonary tuberculosi...
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Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of morbidity and mortality in humans worldwide. Currently, the standard treatment for TB involves multiple antibiotics administered for at least 6 months. Although multiple antibiotics therapy is necessary to prevent the development of drug resistance, the prolonged duration of treatment, combined with toxici...
متن کامل[Extrapulmonary tuberculosis].
Although the respiratory tract is the major site for tuberculous lesions, all organs can be affected. The authors review the clinical files of 25 patients admitted to our Department with lung and/or pleural tuberculous disease, confirmed by bacteriology or histopathology, who simultaneously suffered from tuberculosis in other organs. We included 20 men and 5 women, aged from 10 to 74 years (mea...
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ژورنال
عنوان ژورنال: Cytokine
سال: 2021
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2021.155499